PBSoft took part in the German-Russian Forum Biotechnology 2009 «Perspectives of Bilateral and European Cooperation»Our company was represented in the person of its director Dr. Vladimir Ivanisenko with the oral talk: «ANDCell and ANDNanobiotech: ASSOCIATIVE NETWORK DISCOVERY SYSTEMS IN SYSTEMS BIOLOGY AND NANOBIOTECHNOLOGY».
The presentation was devoted to the recently developed computational prototypes of the ANDCell and ANDNanobiotech systems for automated extraction of knowledge from scientific texts "PubMed abstracts" and databases.
The ANDCell system is targeted on the reconstruction of semantic associative networks in systems biology: molecular genetic interactions, gene regulation events, catalytic processes, proteolysis, polymorphic gene – disease associations, etc. The ANDNanobiotech system is targeted on the area of nanobiotechnology: drug-delivery systems, labeling, diagnostics, treatment, microfluidics, implants, grafts, biosensors and others. Information is extracted with the use of original text mining technology, developed by PBSoft. The ANDCell database contained on the moment of presentation about 5 millions of scientific facts, the ANDNanobiotech database - about 1,5 millions of facts.
The ANDVisio program provides the access to the databases and represent the results in a graphic form of reconstructed associative networks. The vertices of such networks are the molecular genetic objects: genes, proteins, microRNAs, metabolites, cellular components, diseases, processes, nanomaterials and nanobioconstructs while the edges between the vertices represent various types of associations. For molecular interactions and associations, data on the cell types and organisms are represented. The systems provide a user’s friendly interface implemented links to the molecular-genetic databases and the articles from which information was extracted. The systems can be useful for resolving a wide range of tasks in biology, biomedicine, biotechnology and nanobiotechnology.
